Caspase 12 Polyclonal Antibody
Catalogue Number: BS-1105R-BSS
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Lane 1: Mouse Cerebrum lysates; Lane 2: Rat Cerebrum lysates probed with Caspase 12 Polyclonal Antibody, Unconjugated (bs-1105R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C.
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Lane 1: Cerebrum lysates probed with Caspase 12 Polyclonal Antibody, Unconjugated (bs-1105R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
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Lane 1: Mouse Cerebrum lysates; Lane 2: Mouse Heart lysates; Lane 3: Mouse Kidney lysates probed with Caspase 12 Polyclonal Antibody, Unconjugated (bs-1105R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
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Lane 1: Mouse Muscle tissue lysates; Lane 2: Rat Muscle tissue lysates probed with Caspase-12 Polyclonal Antibody, Unconjugated (bs-1105R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
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Formalin-fixed and paraffin embedded rat testis tissue (high fat) labeled with Anti-NPY/Neuropeptide Y Polyclonal Antibody, Unconjugated (bs-1105R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
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Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-Caspase 12 Polyclonal Antibody, Unconjugated (bs-1105R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Caspase-12; CASP-12; Casp12 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse Caspase 12 |
| Application: | ELISA, FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].
Additional Text
Gene Name
CASP12
Gene ID
12364
Uniprot ID
O08736
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
bs-1105R Datasheet
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