Tetanus Toxin heavy chain Antibody

Catalogue Number: BS-11772R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Tetanus toxin; Tentoxylysin; tetX; CTC_p60
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin heavy chain
Application: ELISA, ICC, IF, IHC-P, IHC-Fr

Description

Description: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.

Additional Text

Uniprot ID

P04958

Purification

Protein A purified

Gene ID

24255210

Concentration

1 ug/ul

Gene Name

tetX

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.