TRADD Polyclonal Antibody
Catalogue Number: BS-1202R-BSS
bs-1202R Image
bs-1202R Image
bs-1202R Image
bs-1202R Image
bs-1202R Image
bs-1202R Image
Lane 1: human colon carcinoma lysate; Lane 2: rat brain lysate probed with TRADD Polyclonal Antibody, Unconjugated (bs-1202R) at 1:200 overnight at 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 for 90 min at 37°C.
bs-1202R Image
Formalin-fixed and paraffin embedded rat kidney labeled with Anti-TRADD Polyclonal Antibody, Unconjugated (bs-1202R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
bs-1202R Image
Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-TRADD Polyclonal Antibody, Unconjugated (bs-1202R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
bs-1202R Image
Lane 1: Jurkat cell lysates; Lane 2: MCF-7 cell lysates probed with TRADD Polyclonal Antibody, Unconjugated (bs-1202R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
bs-1202R Image
Cerebrum lysates probed with TRADD Polyclonal Antibody, Unconjugated (bs-1202R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | AA930854; 9130005N23Rik; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain; Tradd |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse of mouse TRADD |
| Application: | ELISA, ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.
Additional Text
Gene Name
TRADD
Uniprot ID
Q3U0V2
Purification
Protein A purified
Gene ID
71609
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
bs-1202R Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations