PKC iota Polyclonal Antibody, Cy5.5 Conjugated

Catalogue Number: BS-12689R-CY5.5-BSS

Manufacturer:	Bioss Inc
Type:	Polyclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	KLH conjugated synthetic peptide derived from human PKC iota/PKCI
Application:	ICC, IF, IHC-P, WB, IHC-Fr

Overview
Datasheets

Description

Description: This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

PRKCI

Uniprot ID

P41743

Gene ID

5584

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

aPKC lambda/iota; aPKC-lambda/iota; Atypical protein kinase C lambda/iota; Atypical protein kinase C-lambda/iota; DXS1179E; KPCI_HUMAN; MGC26534; nPKC iota; nPKC-iota; nPKCiota; PKC lambda; PKCI; PKCiota; PKClambda; PRKC iota; PRKC lambda/iota; PRKC-lambda/iota; PRKCI; Protein kinase C iota; Protein kinase C iota type.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

675nm/694nm

BS-12689R-CY5.5 Datasheet

Price

£390.00

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