Chimaerin 2 Polyclonal Antibody, APC-Cy7 Conjugated
Catalogue Number: BS-13903R-APC-CY7-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | ARHGAP3; BCH; Beta chimerin; Chimaerin2; Chimerin (chimaerin) 2; Chimerin 2; CHN 2; CHN2; CHIO_HUMAN; MGC138360; Rho GTPase activating protein 3; RHOGAP3. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human Chimaerin 2 |
| Application: | WB |
Description
Description: The Chimaerin gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, an SH2 domain and a Rho-GAP domain. This protein has GTPase-activating protein activity which is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Increased expression of this gene is associated with lymphomas and decreased expression of this gene is associated with high-grade gliomas and breast tumors. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Additional Text
Gene Name
CHN2
Gene ID
1124
Uniprot ID
P52757
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
650nm/780nm
BS-13903R-APC-CY7 Datasheet
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