COX6A1 Polyclonal Antibody, FITC Conjugated

Catalogue Number: BS-14007R-FITC-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human COX6A1
Application: ICC, IF, IHC-P, IHC-Fr

Description

Description: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

COX6A1

Uniprot ID

P12074

Gene ID

1337

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

COX VIa L; COX VIa-L; COX6A; COX6A1; COX6AL; CX6A1_HUMAN; Cytochrome c oxidase polypeptide VIa liver; Cytochrome c oxidase polypeptide VIa-liver; Cytochrome c oxidase subunit 6A1; Cytochrome c oxidase subunit 6A1 mitochondrial; Cytochrome C oxidase subunit VIa homolog; Cytochrome c oxidase subunit VIA liver; Cytochrome c oxidase subunit VIa polypeptide 1; Cytochrome c oxidase subunit VIA-liver; MGC104500; mitochondrial.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

494nm/518nm