DEF8 Polyclonal Antibody, Cy5.5 Conjugated
Catalogue Number: BS-14241R-CY5.5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | DEF-8; Def8; Def 8; DEFI8_HUMAN; Differentially expressed in FDCP 8 homolog; FLJ20186; MGC104349. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human DEF8 |
| Application: | IF, WB |
Description
Description: DEF8 is a 512 amino acid protein that is expressed at highest levels in peripheral leukocytes. It is expressed as five isoforms as a result of alternative splicing events. The gene encoding DEF8 maps to chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition that may involve the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Additional Text
Gene ID
54849
Gene Name
DEF8
Uniprot ID
Q6ZN54
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
675nm/694nm
BS-14241R-CY5.5 Datasheet
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