EXD2 Polyclonal Antibody, Cy5 Conjugated

Catalogue Number: BS-14654R-CY5-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:Exonuclease 3'-5' domain-containing protein 2; EXD2; C14orf114; EXDL2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human EXD2
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Additional Text

Gene Name

EXD2

Uniprot ID

Q9NVH0

Gene ID

55218

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

625,650nm/670nm