phospho-KSR1 (Ser404) Polyclonal Antibody
Catalogue Number: BS-16868R-BSS
BS-16868R Image
BS-16868R Image
Hela (H) cells were treated with or without Calyculin A (50nM 30) for 30 min, 25 µg total protein per lane of cell lysates (see on figure) probed with phospho-KSR1 (Ser404) polyclonal antibody, unconjugated (bs-16868R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthesised phosphopeptide derived from human KSR1 around the phosphorylation site of Ser404 |
| Application: | WB |
Description
Description: KSR1 is a molecular scaffold and positive regulator of the Raf/MEK/ERK phosphorylation cascade. It was initially considered to be a protein kinase acting in the Ras pathway. KSR1 is required for maximal ERK activation induced by growth factors and by some cytotoxic agents. In resting cells, phosphorylated KSR1 is cytoplasmic and in stimulated cells, dephosphorylated KSR1 is membrane associated.
Additional Text
Gene ID
8844
Gene Name
KSR1
Uniprot ID
Q8IVT5
Modification
Phosphorylated, Ser404
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Specificity
KSR1 (phospho S404); p-KSR1 (phospho S404); BKSR 1; BKSR1; dKsr; EK 31; EK31; hb; Kinase suppressor of Ras 1; Kinase suppressor of ras; KSR 1; KSR; KSR1; KSR1_HUMAN; Positive Ras signaling mediator family member (86.4 kD); Positive Ras signaling mediator family member; RSU 2; RSU2; SR 31; SR31; Suppressor of activated let 60 Ras SUR3; Suppressor of Ras1 31.
Storage Note
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
BS-16868R Datasheet
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