phospho-HIRA (Thr555) Polyclonal Antibody, PE-Cy7 Conjugated
Catalogue Number: BS-17406R-PE-CY7-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthesised phosphopeptide derived from human HIRA around the phosphorylation site of Thr555 |
| Application: | WB |
Description
Description: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
7290
Gene Name
HIRA
Uniprot ID
P54198
Purification
Protein A purified
Modification
Phosphorylated, Thr555
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Specificity
HIRA (phospho T555); p-HIRA (phospho T555); DGCR1; DGGR 1; DGGR1; DiGeorge critical region gene 1; HIR; HIR histone cell cycle regulation defective homolog A; HIRA; HIRA protein; HIRA_HUMAN; Protein HIRA; TUP 1; TUP1; TUP1 like enhancer of split protein 1; TUP1-like enhancer of split protein 1; TUPLE 1; TUPLE1.
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
488nm/780nm
BS-17406R-PE-CY7 Datasheet
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