Notch3/4 Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated
Catalogue Number: BS-1812R-A750-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse Notch3 |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. It affects the implementation of differentiation, proliferation and apoptotic programs. Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (swissprot).
Additional Text
Gene Name
NOTCH3
Gene ID
4854
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Specificity
hNotch 4;hNotch4;NOTCH 3;NOTCH3;INT 3;INT3;MGC74442;Neurogenic locus notch homolog protein 4;Neurogenic locus notch homolog protein 3;NOTC4_HUMAN;NOTCH-3;NOTCH-4;Notch 4 intracellular domain;Notch homolog 4;NOTCH4 protein;Neurogenic locus notch homolog protein 1; CADASIL; CASIL; Notch homolog 3.
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
bs-1812R-A750 Datasheet
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