Kir4.1 Polyclonal Antibody, APC-Cy5.5 Conjugated

Catalogue Number: BS-2084R-APC-CY5.5-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human Kir4.1
Application: ICC, IF, IHC-P, IHC-Fr

Description

Description: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down?s syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.

Additional Text

Gene Name

KCNJ10

Gene ID

3766

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

ATP dependent inwardly rectying potassium channel Kir4.1; ATP sensitive inward rectier potassium channel 10; ATP-dependent inwardly rectying potassium channel Kir4.1; ATP-sensitive inward rectier potassium channel 10; BIRK10; Glial ATP dependent inwardly rectying potassium channel KIR4.1; Inward rectier K+ channel Kir1.2; Inward rectier K+ channel KIR1.2; Inwardly rectying potassium channel Kir1.2; inwardly rectying subfamily J member 10; KCNJ 10; Kcnj10; KCNJ13 PEN; KIR1.2; KIR4.1; Potassium channel; Potassium channel inwardly rectying subfamily J member 10; Potassium inwardly rectying channel subfamily J member 10; SESAME; IRK10_HUMAN.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

650nm/694nm