CLEC5A Polyclonal Antibody, PE Conjugated
Catalogue Number: BS-2663R-PE-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | Mdl1; Ly100; MDL-1; Clecsf5; C-type lectin domain family 5 member A; C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1; Clec5a |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse CLEC5A |
| Application: | FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.
Additional Text
Gene Name
CLEC5A
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Gene ID
23845
Modification
Unmodified
Uniprot ID
Q9R007
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
496,564nm/578nm
BS-2663R-PE Datasheet
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