Catalogue Number: BS-3980R-CY5-BSS
Manufacturer: | Bioss Inc |
Type: | Polyclonal Primary Antibody - Conjugated |
Alias: | FBP; Fructose-1,6-bisphosphatase 1; FBPase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; Liver FBPase; FBP1 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from human FBP1 |
Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
FBP1
P09467
2203
Protein A purified
1 ug/ul
Polyclonal
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.