Recombinded human Cyclin D1 protein, N-His, APC Conjugated
Catalogue Number: BS-41047P-APC-BSS
| Manufacturer: | Bioss Inc |
| Physical state: | Aqueous |
| Type: | Cell Cycle Proteins |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 500 ug |
Description
Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008].
Additional Text
Gene Name
CCND1
Uniprot ID
P25322
Gene ID
12443
Protein Tag
HIS Tag
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Endotoxin
Not Tested
Short Description
Recombinded human Cyclin D1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1-295/295
BS-41047P-APC Datasheet
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