Recombinant human KCNA3 protein, N-Trx&His, APC Conjugated

Catalogue Number: BS-42284P-APC-BSS

Manufacturer:Bioss Inc
Physical state:Aqueous
Type:Protein - Conjugated
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 500 ug

Description

Description: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008].

Additional Text

Uniprot ID

P22001

Gene ID

3738

Gene Name

KCNA3

Protein Tag

TRX-HIS Tag

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Endotoxin

Not Tested

Short Description

Recombinant human KCNA3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-234/575

Price
£248.00


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