Recombinant human ULK1 protein, N-His, APC Conjugated
Catalogue Number: BS-42338P-APC-BSS
| Manufacturer: | Bioss Inc |
| Physical state: | Aqueous |
| Type: | Protein - Conjugated |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 500 ug |
Description
Description: ULK1 belongs to the serine/threonine protein kinase family. It is involved in axon growth and plays an essential role in neurite branching during sensory axon outgrowth. Knockdown of ULK1 results in impaired endocytosis of nerve growth factor (NGF), excessive axon arborization, and severely stunted axon elongation indicating that ULK1 mediates a non clathrin coated endocytosis in sensory growth cones. Knockdown of ULK1 also inhibits the autophagic response. It appears to act as a convergence point for multiple signals that regulate autophagy, and in turn interacts with a large number of autophagy related (Atg) proteins.
Additional Text
Uniprot ID
O75385
Gene ID
8408
Gene Name
ULK1
Protein Tag
HIS Tag
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Endotoxin
Not Tested
Short Description
Recombinant human ULK1 protein in E.coli with N-His. It contains the amino acid sequence of 17-466/1050
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