Recombinant human ADAMTS5 protei, N-His, APC Conjugated
Catalogue Number: BS-42469P-APC-BSS
| Manufacturer: | Bioss Inc |
| Physical state: | Aqueous |
| Type: | Protein - Conjugated |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 500 ug |
Description
Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]
Additional Text
Gene Name
ADAMTS5
Uniprot ID
Q9UNA0
Gene ID
11096
Protein Tag
HIS Tag
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Endotoxin
Not Tested
Short Description
Recombinant human ADAMTS5 protei in E.coli with N-His. It contains the amino acid sequence of 485-624/930
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