Recombinant mouse CD40L protein, N-His (HEK293)
Catalogue Number: BS-43030P-BSS
| Manufacturer: | Bioss Inc |
| Type: | Cytokines |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Blue Ice |
| Storage Condition: | -70°C |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
Additional Text
Gene Name
CD40LG
Gene ID
21947
Uniprot ID
P27548
Protein Tag
HIS Tag
Storage Note
The product should be stored at -70°C or -20°C.
Short Description
Recombinant mouse CD40L protein, N-His (HEK293) protein is expressed in HEK293 with N-His. It contains the amino acid sequence of 112-260/260.
Endotoxin
Not Tested
SUPPORT
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PRODUCT
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DELIVERY
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