Recombinant human IL-7Ra protein, C-His (HEK293)
Catalogue Number: BS-43043P-BSS
| Manufacturer: | Bioss Inc |
| Type: | Other Recombinant Protein |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Blue Ice |
| Storage Condition: | -70°C |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA |
Description
Description: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
Additional Text
Gene ID
3575
Uniprot ID
P16871
Gene Name
IL7R
Protein Tag
HIS Tag
Storage Note
The product should be stored at -70°C or -20°C.
Short Description
Recombinant human IL-7Ra protein, C-His (HEK293) protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 21-239/459.
Endotoxin
Not Tested
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