Recombinant human TGFBR2 protein, C-hFc (HEK293)

Catalogue Number: BS-43523P-BSS

Manufacturer:Bioss Inc
Type:Protein Kinases
Host Cell:HEK293 cells
Shipping Condition:Blue Ice
Storage Condition:-70°C
Unit(s): 100 ug, 500 ug
Application: ELISA

Description

Description: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Additional Text

Gene Name

TGFBR2

Uniprot ID

P37173

Gene ID

7048

Protein Tag

hFC Tag

Storage Note

The product should be stored at -70°C or -20°C.

Short Description

Recombinant human TGFBR2 protein, C-hFc (HEK293) protein is expressed in HEK293 with C-hFc. It contains the amino acid sequence of 23-159/567.

Endotoxin

Not Tested

Price
£248.00


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