phospho-Caspase 6 (Ser257) Polyclonal Antibody, APC-Cy7 Conjugated
Catalogue Number: BS-5240R-APC-CY7-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257 |
| Application: | FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.
Additional Text
Gene Name
CASP6
Gene ID
839
Modification
Phosphorylated, Ser257
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Specificity
Apoptosis-related cysteine protein; Apoptosis Related Cysteine Protease; Apoptotic cysteine protease MCH2; Apoptotic protease MCH 2; Apoptotic protease MCH2; Casp 6; Casp6; Caspase 6 apoptosis related cysteine protease; Caspase 6 precursor; Caspase6; Human cysteine protease Mch2 isoform alpha; Mch 2; Mch2; CASP6_HUMAN.
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
650nm/780nm
BS-5240R-APC-CY7 Datasheet
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