IL-1R1 (Tyr496) Polyclonal Antibody

Catalogue Number: BS-5394R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Polyclonal Primary Antibody - Unconjugated
Alias:P8; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha; Interleukin-1 receptor type 1; IL-1R-1; IL-1RT-1; IL-1RT1; CD121 antigen-like family member A; Interleukin-1 receptor alpha; Interleukin-1 receptor type I; IL1R1; IL1RT1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 20 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic phosphopeptide derived from human IL-1R1 around the phosphorylation site of Tyr496
Application: ELISA, FC, ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Additional Text

Gene ID

3554

Gene Name

IL1R1

Uniprot ID

P14778

Modification

Phosphorylated, Tyr496

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Storage Note

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.