phospho-PTPN6 (Tyr536) Polyclonal Antibody, Cy3 Conjugated
Catalogue Number: BS-5577R-CY3-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic phosphopeptide derived from human PTPN6 around the phosphorylation site of Tyr536 [SE(p-Y)GN] |
| Application: | FC, ICC, IF, IHC-P, WB |
Description
Description: SHP1 is a member of the non receptor protein tyrosine phosphatase subfamily. The PTP family comprises of at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is cytosolic. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. SHP1 is implicated in the control of tyrosine kinase signalling pathways in cellular proliferation, with a potential role in cancer.
Additional Text
Gene ID
5777
Gene Name
PTPN6
Uniprot ID
P29350
Modification
Phosphorylated, Tyr536
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Specificity
SHP-1Tyr536; PTPN6phospho Y536; SHP1phospho Y536; 70 kda SHP1L protein; HCP; HCPH; Hematopoietic cell phosphatase; Hematopoietic cell protein tyrosine phosphatase; Hematopoietic cell protein-tyrosine phosphatase; HPTP1C; Protein tyrosine phosphatase 1C; Protein tyrosine phosphatase non receptor type 6; Protein tyrosine phosphatase SHP1; PTP1C; PTPN6; SH PTP 1; SHP1; SHP1L; PTN6_HUMAN.
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
512,550nm/570,615nm
bs-5577R-Cy3 Datasheet
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