Adenovirus 5 E1A Polyclonal Antibody

Catalogue Number: BS-6136R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Adenovirus early E1A protein; Control protein E1A; E1A; Early E1A protein; Human adenovirus type 5; Human adenovirus C; pfam02703; E1A_ADE05.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A
Application: ELISA, ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.

Additional Text

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Uniprot ID

P03255

Modification

Unmodified

Storage Note

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.