PTK6 Polyclonal Antibody, AbBy Fluor-555 Conjugated

Catalogue Number: BS-6266R-BF555-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:Breast tumor kinase; Breast tumour kinase; Protein tyrosine kinase 6; PTK6; Tyrosine protein kinase BRK; PTK6_HUMAN.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human Brk/PTK6
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.

Additional Text

Gene ID

5753

Gene Name

PTK6

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

553nm/568nm