UACA Polyclonal Antibody, AbBy Fluor-680 Conjugated
Catalogue Number: BS-6308R-BF680-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | NUCLING; Uveal autoantigen with coiled-coil domains and ankyrin repeats; UACA; KIAA1561 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human UACA |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
Additional Text
Gene ID
55075
Gene Name
UACA
Uniprot ID
Q9BZF9
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
679nm/702nm
BS-6308R-BF680 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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