ERCC6L Polyclonal Antibody, AbBy Fluor-594 Conjugated
Catalogue Number: BS-6380R-BF594-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human ERCC6L |
| Application: | ICC, IF, IHC-P, IHC-Fr |
Description
Description: ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
Additional Text
Gene Name
ERCC6L
Gene ID
54821
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Specificity
ATP dependent helicase ERCC6 like; DNA excision repair protein ERCC 6 like; ERCC 6L; ERCC6L; Excision repair cross complementing rodent repair deficiency complementation group 6 like; Excision repair protein ERCC6 like; FLJ20105; MGC131695; PICH; Plk1 interacting checkpoint helicase; SNF2/RAD54 family protein; Tumor antigen BJ HCC 15; ERC6L_HUMAN.
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
590nm/617nm
BS-6380R-BF594 Datasheet
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