RLLM1 Polyclonal Antibody, AbBy Fluor-594 Conjugated
Catalogue Number: BS-6514R-BF594-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | CGI 99; CGI99; CLE; Homeobox prox 1; RLLM1; Chromosome 14 open reading frame 166; CLE7; LCRP369; RLL mot containing 1; CN166_HUMAN. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human RLLM1/C14orf166 |
| Application: | ICC, IF, IHC-P, IHC-Fr |
Description
Description: CGI-99 is a 244 amino acid protein that localizes to the nucleus, as well as to the cytoplasm, and belongs to the UPF0568 family. Expressed in a variety of tissues with particularly high levels in heart and skeletal muscle, CGI-99 functions as a homodimer that interacts with Ninein and is thought to regulate Ninein function. CGI-99 is overexpressed in brain tumor tissue, suggesting a role in tumor development and metastasis. The gene encoding CGI-99 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Additional Text
Gene ID
51637
Purification
Protein A purified
Concentration
1 ug/ul
Gene Name
RTRAF
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
590nm/617nm
BS-6514R-BF594 Datasheet
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