Fractin Antibody
Catalogue Number: BS-70093R-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Fragment of actin, actin cleavage product |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide corresponding to amino acid residues from the C-terminal region of the 32 kDa actin fragment. |
| Application: | IHC-P, WB, IHC |
Description
Description: Fractin (fragment of actin) is a caspase-specific cleavage product of actin and serves as a novel marker of apoptosis-related events. The antibody has been shown to detect the processes and cell bodies of degenerating neurons and plaque-associated microglia in Alzheimer's disease (Yang et al., 1998). It has recently been reported that Fractin may have a functional role in apoptotic signaling in oligodendrocytes (Schulz, R., et al., Glia, 2009, in press).
Additional Text
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Purification
Neat whole antiserum
BS-70093R Datasheet
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