Periostin pan Antibody

Catalogue Number: BS-70220R-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide corresponding to amino acid residues from the fasciclin domain 1 of mouse periostin.
Application: IHC-P, WB, IHC

Description

Description: Periostin is a matricellular protein, i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins, the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading (Kruzynska-Frejtag A. et al., 2004). Periostin has recently been shown to promote collagen fibrogenesis, inhibit differentiation of progenitor cells into cardiomyocytes and to be essential in maintaining the biomechanical properties of the adult myocardium (Norris et al., 2008)

Additional Text

Gene Name

POSTN

Gene ID

50706

Uniprot ID

Q62009

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

Fasciclin-I like antibody, MGC119510 antibody, MGC119511 antibody, OSF 2 antibody, OSF-2 antibody, OSF2 antibody, Osteoblast specific factor 2 (fasciclin I like) antibody, Osteoblast specific factor 2 antibody, Osteoblast specific factor antibody, Osteoblast-specific factor 2 antibody, PDLPOSTN antibody, Periodontal ligament specific periostin antibody, Periostin antibody, Periostin isoform thy2 antibody, Periostin isoform thy4 antibody, Periostin isoform thy6 antibody, Periostin isoform thy8 antibody, Periostin osteoblast specific factor antibody, PN antibody, POSTN antibody, POSTN_HUMAN antibody, RP11 412K4.1 antibody

Storage Note

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.