Prosurfactant Protein C Antibody

Catalogue Number: BS-70233R-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide from the N-terminal region of mouse Prosurfactant Protein C.
Application: IHC-P, IHC

Description

Description: Pulmonary surfactant Protein C (SP-C) is one of 4 distinct surfactant proteins; SP-A, SP-B, SP-C and SP-D. SP-C is produced by proteolytic cleavage of a larger precursor known as Prosurfactant Protein C which is expressed exclusively in the lungs and widely used as a marker for alveolar type 2 epithelial cells. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency and are associated with interstitial lung disease in older infants, children, and adults.

Additional Text

Uniprot ID

P21841

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Specificity

BRICD6 antibody, BRICHOS domain containing 6 antibody, PSP C antibody, PSPC antibody, PSPC_HUMAN antibody, Pulmonary surfactant apoprotein 2 antibody, Pulmonary surfactant apoprotein PSP C antibody, pulmonary surfactant apoprotein-2 SP-C antibody, Pulmonary surfactant associated protein C antibody, Pulmonary surfactant associated proteolipid SPL pVal antibody, Pulmonary surfactant associated proteolipid SPL(Val) antibody, Pulmonary surfactant protein SP5 antibody, Pulmonary surfactant-associated protein C antibody, Pulmonary surfactant-associated proteolipid SPL(Val) antibody, SFTP 2 antibody, SFTP2 antibody, SFTPC antibody, SFTPC surfactant pulmonary associated protein C antibody, SMDP2 antibody, SP 5 antibody, SP C antibody, SP-C antibody, SP5 antibody, SPC antibody, Surfactant associated protein pulmonary 2 antibody, Surfactant protein c antibody, Surfactant proteolipid SPL-pVal antibody, Surfactant pulmonary associated protein C antibody