FAM161B Polyclonal Antibody, AbBy Fluor-680 Conjugated

Catalogue Number: BS-8226R-BF680-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:C14orf44; Chromosome 14 open reading frame 44; Family with sequence similarity 161, member B; FLJ31697; Hypothetical protein LOC145483; Protein FAM161B; F161B_HUMAN.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human FAM161B
Application: ICC, IF, IHC-P, IHC-Fr

Description

Description: FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer?s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder 1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.

Additional Text

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

679nm/702nm