CTDSPL Polyclonal Antibody, RBITC Conjugated

Catalogue Number: BS-8241R-RBITC-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human CTDSPL
Application: FC, ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.

Additional Text

Gene ID

10217

Gene Name

CTDSPL

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; CTD small phosphatase-like protein; CTDSL_HUMAN; CTDSP-like; Ctdspl; hYA22; N-like protein; NLI-interacting factor 1; Nuclear LIM interactor-interacting factor 1; Protein YA22; RBSP3; SCP3; Small C-terminal domain phosphatase 3; Small CTD phosphatase 3.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

570nm/595nm