GIMAP3 Polyclonal Antibody, APC-Cy5.5 Conjugated
Catalogue Number: BS-8269R-APC-CY5.5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | GTPase, IMAP family member 3 pseudogene; Ian4; Gimap5; 2010110D23Rik; GIMAP 3; GIMAP3; GTPase IMAP family member 3; GTPase of the immune associated protein 3; Immune associated nucleotide 4; Immunity associated nucleotide 4 protein. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from mouse GIMAP3 |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: GIMAP3p is a murine mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The IAN/GIMAP family consists of GTP-binding proteins that share a unique primary structure and whose expression is finely regulated by T-cell receptor signals. Recent studies have shown that IAN/GIMAP family proteins crucially regulate the survival of T cells during development, selection and homeostasis, and are possibly linked to the onset of T-lymphopenia, leukemia and autoimmunity. IAN/GIMAP family proteins might also take part in mitochondrial regulation of lymphocyte apoptosis by interacting with Bcl-2 family proteins. The human GIMAP (GTPase of the immunity-associated protein) gene family includes seven functional members residing on (human) chromosome 7q36.1 and one pseudogene (hGIMAP3).
Additional Text
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
650nm/694nm
BS-8269R-APC-CY5.5 Datasheet
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