RNF160 Polyclonal Antibody, APC-Cy5.5 Conjugated

Catalogue Number: BS-8376R-APC-CY5.5-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:RNF160; ZNF294; C21orf10; C21orf98; E3 ubiquitin-protein ligase listerin; RING finger protein 160; Zinc finger protein 294; LTN1; KIAA0714; HSPC087
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human RNF160/ZNF294
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).

Additional Text

Gene ID

26046

Gene Name

LTN1

Uniprot ID

O94822

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

650nm/694nm