phospho-Cdc25B (Ser149) Polyclonal Antibody, AbBy Fluor-488 Conjugated

Catalogue Number: BS-8445R-BF488-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:AI604853; M-phase inducer phosphatase 2; Dual specificity phosphatase Cdc25B; Cdc25b; Cdc25m2
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse Cdc25B around the phosphorylation site of Ser149
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity (By similarity).

Additional Text

Gene Name

CDC25B

Gene ID

12531

Uniprot ID

P30306

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Phosphorylated, Ser149

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

499nm/519nm