FNDC1 Polyclonal Antibody, AbBy Fluor-594 Conjugated

Catalogue Number: BS-8460R-BF594-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:Activation-associated cDNA protein; AGS8; Expressed in synovial lining protein; fibronectin type III domain containing 2; Fibronectin type III domain-containing protein 1; FNDC1; FNDC1_HUMAN; FNDC2; MEL4B3.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human FNDC1
Application: ICC, IF, IHC-P, IHC-Fr

Description

Description: FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.

Additional Text

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Gene ID

84624

Gene Name

FNDC1

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

590nm/617nm