FBXL21 Polyclonal Antibody, AbBy Fluor-488 Conjugated
Catalogue Number: BS-8476R-BF488-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human FBXL21/FBL3B |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.
Additional Text
Gene ID
26223
Purification
Protein A purified
Concentration
1 ug/ul
Gene Name
FBXL21P
Antibody Clonality
Polyclonal
Modification
Unmodified
Specificity
F box and leucine rich repeat protein 21; F box and leucine rich repeat protein 3 pseudogene; F box and leucine rich repeat protein 3B; F box protein Fbl3b; F box/LRR repeat protein 21; F box/LRR repeat protein 3B; Fbl 21; FBXL 21; FBXL-21; FBL 3; FBL 3B; Fbl21; FBL3; FBL-3B; FBL 3B; FBL3B; FBXL 21; FBXL 3B; FBXL 3P; FBXL3B; FBXL3P; MGC120237; FXL21_HUMAN.
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
499nm/519nm
BS-8476R-BF488 Datasheet
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