MtTF1/TFAM Polyclonal Antibody, RBITC Conjugated
Catalogue Number: BS-8520R-RBITC-BSS
| Manufacturer: | Bioss Inc |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | TCF6; MTTF1; MTTFA; TCF6L1; TCF6L2; TCF6L3; Transcription factor A, mitochondrial; Mitochondrial transcription factor 1; Transcription factor 6; TCF-6; Transcription factor 6-like 2; TFAM |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human MtTF1 |
| Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description
Description: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
Additional Text
Gene Name
TFAM
Uniprot ID
Q00059
Gene ID
7019
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Polyclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
570nm/595nm
BS-8520R-RBITC Datasheet
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