VANGL1 Polyclonal Antibody, AbBy Fluor-680 Conjugated

Catalogue Number: BS-8527R-BF680-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:Loop tail protein 2 homolog; Loop-tail protein 2 homolog; LPP2; MGC5338; STB2; STBM2; Strabismus 2; Van Gogh like protein 1; Van Gogh-like protein 1; vang like 1 van gogh, Drosophila; Vang like protein 1; Vang-like protein 1; VANG1_HUMAN; VANGL 1; Vangl1.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human VANGL1/LPP2
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: The Vang family of proteins are integral membrane proteins that are homologues of the Drosophila tissue polarity gene strabismus. The gene encoding for Van Gogh-like protein 1 (Vangl1), also designated Strabismus 2 (STB2), localizes to human chromosome 1p11-p13.1. Van Gogh-like protein 2 (Vangl2), also designated Strabismus 1 (STB1), localizes to chromosome 1q22-q23. Vangl1 is expressed primarily in testis and ovary, but is also expressed in gastric and pancreatic cancer. Vangl proteins play a key developmental role in establishing planar cell polarity (PCP) and in regulating convergent extension (CE) movements during embryogenesis. Vangl1 and Vangl2 are both downregulated in several cancer cell lines and primary tumors.

Additional Text

Gene ID

8612

Purification

Protein A purified

Concentration

1 ug/ul

Gene Name

PLPP2

Antibody Clonality

Polyclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

679nm/702nm