CBR1 Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated

Catalogue Number: BS-8632R-A680-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human CBR1
Application: ICC, IF, IHC-P, WB, IHC-Fr

Description

Description: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Additional Text

Gene ID

873

Gene Name

CBR1

Uniprot ID

P16152

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Unmodified

Specificity

Carbonyl reductase [NADPH] 1; CBR1; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; Prostaglandin-E(2) 9-reductase (EC:1.1.1.189); Short chain dehydrogenase/reductase family 21C member 1; CBR; CRN; SDR21C1

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.