phospho-IRS1 (Tyr1179) Polyclonal Antibody, AbBy Fluor-680 Conjugated

Catalogue Number: BS-8709R-BF680-BSS

Manufacturer:Bioss Inc
Type:Polyclonal Primary Antibody - Conjugated
Alias:IRS1 (phospho S1179); p-IRS1 (phospho S1179); p-IRS1; IRS1(phospho-Ser1179); HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS-1; IRS 1; IRS1; OTTHUMP00000164234; IRS1_HUMAN.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser1179.
Application: FC, ICC, IF

Description

Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

Additional Text

Gene Name

IRS1

Gene ID

3667

Uniprot ID

P35568

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Polyclonal

Modification

Phosphorylated, Tyr1179

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

679nm/702nm