G-CSF(2C7) Monoclonal Antibody, APC-Cy5.5 Conjugated

Catalogue Number: BSM-10808M-APC-CY5.5-BSS

Manufacturer:	Bioss Inc
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	2C7
Isotype:	IgG
Immunogen:	KLH conjugated synthetic peptide derived from human G-CSF
Application:	IF, WB

Overview
Datasheets

Description

Description: Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell proliferation and differentiation. G-CSF was isolated initially as a factor supporting the growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage lineage are among the most prominent sources of G-CSF, but this factor can also be produced by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-Gamma. G-CSF is likely to play a role in the basal regulation of neutrophil production, and also functions as a primary regulatory factor controlling the neutrophil response to inflammatory stimuli. Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the body.

Additional Text

Gene ID

1440

Gene Name

CSF3

Uniprot ID

P09919

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Specificity

Colony stimulating factor 3 (granulocyte); CSF 3; CSF beta; CSF3; Csfg; Filgrastim; GCSA; GCSF; Granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; Granulocyte Colony Stimulating Factors 3; CSF3_HUMAN.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

650nm/694nm

BSM-10808M-APC-CY5.5 Datasheet

Price

£486.00

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