Morphine(2F11) Monoclonal Antibody, AbBy Fluor-680 Conjugated

Catalogue Number: BSM-2129M-BF680-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Conjugated
Alias:Morphine 6.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2F11
Isotype: IgG
Immunogen: KLH conjugated Morphine molecular modified
Application: IF, WB

Description

Description: Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.

Additional Text

Purification

Protein G purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

679nm/702nm