Trx-Tag Monoclonal Antibody, APC-Cy7 Conjugated

Catalogue Number: BSM-33018M-APC-CY7-BSS

Manufacturer:Bioss Inc
Type:Tag antibodies
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 7G10
Isotype: IgG
Immunogen: Recombinant human Thioredoxin
Application: WB

Description

Description: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Additional Text

Gene Name

TXN

Uniprot ID

P10599

Gene ID

7295

Purification

Protein G purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Specificity

Thioredoxin; ADF; Surface associated sulphydryl protein; Thioredoxin-1; Thioredoxin 1; Thioredoxin1; TXN protein; ADF; ATL derived factor; DKFZp686B1993; MGC61975; SASP; Surface associated sulphydryl protein; Surface-associated sulphydryl protein; TRDX; TRX 1; TRX; TRX1; TXN; TXN; ATL derived factor; ATL-derived factor; THIO_HUMAN; zgc:92903; Trx-Tag.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

650nm/780nm