Bcl-2 Monoclonal Antibody, APC-Cy7 Conjugated

Catalogue Number: BSM-33047M-APC-CY7-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 8B5
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human Bcl2
Application: WB

Description

Description: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Additional Text

Gene Name

BCL2

Gene ID

596

Uniprot ID

P10415

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Specificity

Apoptosis regulator Bcl 2; Apoptosis regulator Bcl2; AW986256; B cell CLL/lymphoma 2; B cell leukemia/lymphoma 2; B cell lymphoma 2; Bcl 2; Bcl-2; Bcl2; BCL2 protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; Leukemia/lymphoma, B-cell, 2; Oncogene B-cell leukemia 2; BCL2_HUMAN.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

650nm/780nm