Fibronectin (1B9) Monoclonal Antibody , ALEXA FLUOR® 680 Conjugated
Catalogue Number: BSM-33143M-A680-BSS
| Manufacturer: | Bioss Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Fibronectin; FN1; Cold-insoluble globulin; CIG |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 1B9 |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human Fibronectin |
| Application: | IF, IHC-P, WB |
Description
Description: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
Additional Text
Gene Name
FN1
Gene ID
2335
Uniprot ID
P02751
Purification
Protein G purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
bsm-33143M-A680 Datasheet
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