Bax Monoclonal Antibody, APC-Cy5.5 Conjugated

Catalogue Number: BSM-33279M-APC-CY5.5-BSS

Manufacturer:	Bioss Inc
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	8H12
Isotype:	IgG
Immunogen:	KLH conjugated synthetic peptide derived from human Bax
Application:	ICC, IF, IHC-P, WB

Overview
Datasheets

Description

Description: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].

Additional Text

Gene Name

BAX

Gene ID

581

Uniprot ID

Q07812

Purification

Protein G purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Specificity

apoptosis regulator BAX; Apoptosis regulator BAX cytoplasmic isoform beta; Apoptosis regulator BAX membrane isoform alpha; Bax isoform psi; BAX protein cytoplasmic isoform delta; Bax protein cytoplasmic isoform delta. antibody Bax protein cytoplasmic isoform gamma; Bax zeta; Bax-protein; Bcl-2-like protein 4; BCL2 associated X protein; BCL2L4; BAX_HUMAN.

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

650nm/694nm

BSM-33279M-APC-CY5.5 Datasheet

Price

£486.00

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Quantity
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