Human S100B (7F3) Monoclonal Antibody

Catalogue Number: BSM-41680M-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 7F3
Isotype: IgG1
Immunogen: Recombinant human S100B protein
Application: ELISA, LF

Description

Description: S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Additional Text

Gene Name

S100B

Gene ID

6285

Uniprot ID

P04271

Purification

Protein A purified

Antibody Clonality

Monoclonal

Modification

Unmodified

Concentration

1 mg/ml

Specificity

NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium binding protein beta chain; S100 calcium-binding protein B; S100 protein beta chain; S100B_HUMAN; S100beta; S100 _; S100-_; S100_.

Storage Note

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.